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De helpdesk bevat meer dan 1500 vragen en antwoorden over diverse galenische topics, allemaal aangeleverd door Prof. R. Kinget.
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What is the best way to process Fasigyn tablets into a 10 ml syrup for a single dose for a 2-year-old child, and which flavor is the best choice?
What advice can you provide regarding the preparation of econazole nitrate 1% eye drops?
How can a preparation consisting of 0.2 g hydrocortisone acetate, 0.5 g Carbopol 940, 2 g glycerol, NaOH 1N q.s., and water up to 30 g be made without the hydrocortisone acetate hydrolyzing, given that NaOH is added to neutralize the gel for viscosity but maximum viscosity requires a pH of 7 to 8 while the acetate ester is most stable at pH 5.5, and would it be better to use a different type of Carbopol due to benzene residues?
What is the formula for preparing a 1 mg/ml diazepam solution that can be administered via a feeding tube to a 3-year-old child?
How can I process three Fasigyn pills, which are intended to be taken all at once, into a suspension that camouflages their very bad taste, given that a doctor requested an alternative form because the child cannot swallow well and filling the powder into capsules would require swallowing 12 units?
How should I prepare eye drops containing 300 mg each of potassium iodide and sodium iodide with 30 mg of HPMC for a 10 ml collyrium, given that HPMC swells in water and makes the solution impossible to filter through a 0.22 micrometer membrane filter, thereby rendering filtration after addition useless; is the current method of placing the salts and HPMC together in an eye drop bottle and adding sterile water from an ampoule via a syringe and needle appropriate?
What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?
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