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The compounding helpdesk contains more than 1500 questions and answers on various galenic topics, all provided by Prof. R. Kinget.
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How can clumping be avoided during the preparation of 30 suppositories, each containing 0.5 g paracetamol, 3 mg ergotamine tartrate, 6 mg belladonna extract, 150 mg butalbital, 100 mg caffeine, and 10 drops of laudanum, and is this clumping caused by the presence of the laudanum drops?
Is it possible to formulate an ointment or cream containing a cephalosporine for a dog with an anal inflammation, given that the germ is only sensitive to cephalosporines and no commercial specialty product is available, despite Dutch pharmaceutical sites mentioning its external use in creams and lotions without providing a specific formula?
Is there a better solution to obtain a firmer cream for a preparation containing 1 ml chlorhexidine digluconate, 3 g salicylic acid, 5 g undecylenic acid, 6 g benzoic acid, 20 g zinc undecylenate, and ava-cream up to 100 g, given that adding Arlacel still results in a relatively fluid ointment?
How can precipitation be avoided in the following composition: 12 g podophyllin, 10 g collodion, and 70% isopropanol up to 50 ml?
Can erythrosine be used as a colorant in a 0.1% methadone solution in aqua conservans, and what concentration would you recommend?
What is the shelf life of a iodine solution with a concentration of 50 micrograms per milliliter?
What is a suitable alternative for Betnesol enemas for a patient with colitis, given that these are no longer commercially available and a corticosteroid enema is preferred since 5-ASA does not provide the desired results?
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