How can a homogeneous powder mixture be obtained from a formulation containing 1 g hexachlorophene, 0.5 g menthol, 1 g phenol, 5 g crotamiton, 10 g magnesium stearate, and talc up to 100 g, given that the current preparation method—gradually adding crotamiton to the talc, mixing in hexachlorophene and magnesium stearate, and then adding a mixture of menthol and phenol rubbed together in a mortar—results in a grainy mixture of particles and powder?

How can a stable lotion be prepared for a formulation containing 5% salicylic acid, 5% Tween 80, and 0.05% clobetasol propionate in water up to 100 ml, given that the current preparation method is causing problems?

Is it possible to process Broncho-Vaxom for children into a liquid form, given that the 3-year-old patient has difficulty swallowing capsules and a suspension is being considered despite some doubts?

What reaction causes the powder in a capsule containing 250 mg calcium carbonate, 139.665 mg calcium bisglycinate 17.9%, 0.75 mg chromium picolinate 12%, 0.065 mg potassium iodide, 138.89 mg tri-potassium citrate, 2.04 mg copper bisglycinate 18.4% soluble, 14.55 mg manganese bisglycinate (Mn 17.2%), 12.5 mg sodium molybdate 0.2%, 10 mg selenomethionine 5000 mcg/g, 56.25 mg zinc mono L-methionine, 5 mg vitamin K2 MK-7 MenaQ7 0.2%, 90 mg vitamin C (ascorbic acid), 50 mg silicon dioxide, and 15 mg magnesium stearate Frutarom to turn black?

What is the most appropriate approach for dispensing capsules prescribed as 75 mg zinc acetate when zinc acetate anhydrous (M = 183.46) is unavailable: should they be dispensed as 75 mg zinc acetate dihydrate (M = 219.46) without accounting for crystal water (similar to morphine hydrochloride), or should the dose be adjusted to 90 mg zinc acetate dihydrate to maintain the equivalent zinc content?

What is the best ingredient to replace hexachlorophene in a teat ointment containing 0.15 g hexachlorophene, 0.15 g hydrocortisone acetate, 0.15 g lidocaine HCl, 0.3 g diphenhydramine HCl, 22.35 g PEG 400, and PEG 4000 up to 30 g, given that hexachlorophene has been removed from the market due to toxicity?

Why does a dental gel composed of 37% phosphoric acid, 0.1% sodium lauryl sulfate, 0.001% methylene blue, and aqua ad 100%, which achieves a semi-liquid consistency using 2% hypromellose, become liquid over time, and is this instability caused by the influence of the acid?