Which solution can be used for opiate titration?

Is there a significant difference between using isosorbide dinitrate and isosorbide mononitrate for the treatment of anal fissures in a compounded preparation consisting of 1 g isosorbide (di)nitrate 40%, 37 g white vaseline, 7.5 g liquid paraffin, 3.5 g wool fat, and water up to 50 g, given that the mononitrate is a metabolite of the dinitrate and only the mononitrate is mentioned in Martindale for this indication?

How can the following preparation, which liquefies despite the addition of extra base, be successfully compounded: 10 g mephenesin, 1 g methyl nicotinate, 40 g PEG 1500, and 4% carbopol gel up to 100 g?

What is the best way to prepare 300 mg potassium iodide capsules?

Do you have data regarding the magistral preparation of phenytoin suppositories, including the best suppository base to use and information on phenytoin serum concentrations following rectal administration?

What is the most appropriate way to prepare 500 mg chloral hydrate in capsules, given its harmful effect on the stomach and the fact that the patient refuses chloral hydrate syrup?

According to the drug control service in Liège, some drug users are reportedly using vitamin C to precipitate carboxymethylcellulose—which is added to methadone capsules to prevent the preparation of an injectable extract—thereby recovering approximately 15% of the methadone; is this chemically possible, and if so, is there a countermeasure against it?