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The compounding helpdesk contains more than 1500 questions and answers on various galenic topics, all provided by Prof. R. Kinget.
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What is the recommended preparation for vitamin C eye drops, intended as a cicatrizing agent, given a prescription for 1 g of vitamin C in 10 g of water where the physician's request to make it physiological is impossible, and the pharmacist has already neutralized 600 mg of vitamin C with 210 mg of sodium bicarbonate to reach a pH of 5, resulting in a slightly hypertonic but acceptable solution?
Could you please provide a preparation instruction for nasal administration of midazolam?
What is a suitable alternative to replace Miglyol 812 in the production of bath oil, given that its high cost of 60 euros per liter is a problem?
What is the best filler to use for a prescription of 40 enteric-coated capsules containing 4 different essential oils at 25 mg each per capsule (Aerosil, magnesium stearate, or a specific mixture)?
What is the recommended preparation method for a first formulation consisting of 6 g coal tar saponin and 3 g salicylic acid in eucerin with water up to 100 g, and a second formulation consisting of 2 g salicylic acid and 20 g propylene glycol in water up to 200 g?
What is the most appropriate way to prepare a bromazepam syrup for an adult patient who normally takes 12 mg Lexotan but currently has swallowing difficulties, given a proposed formulation of 240 mg bromazepam in 100 ml syrup (12 mg per coffee spoon) where the drug did not fully dissolve in 5 ml ethanol and was subsequently kept in suspension using 1% methylcellulose 400 without flavor correction?
Is it possible to prepare a dithranol washable emulsion as a stock preparation without the dithranol, so that it only needs to be added at the time of dispensing, given a stock formula consisting of 20.5% cetiol V, 15% cetomacrogol cream, 15% liquid paraffin, 1% salicylic acid, 0.05% ascorbic acid, and water up to 100g?
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