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The compounding helpdesk contains more than 1500 questions and answers on various galenic topics, all provided by Prof. R. Kinget.
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What are some tips for preparing chloramphenicol eye drops with a preservative but without cortisone, as requested by an ophthalmologist?
What is the best way to prepare a prescription for 5% minoxidil using 10 g of 70% alcohol, 1 g of Tween 20, 5 g of propylene glycol, 20 g of isopropyl alcohol, and 14 g of water?
How can the preparation of a frictio decontrahens NF5 containing 2 g lidocaine HCl, 2 g methyl nicotinate, 10 g capsicum tincture, 10 g chlorzoxazone, and 200 ml isopropyl alcohol be improved, given that dissolving all components in isopropyl alcohol and adding the capsicum tincture last results in a cloudy solution with easily suspendable sediment?
Why are white flakes visible after incorporating hydrocortisone acetate 0.5% and chlorhexidine digluconate 0.5% into a carbopol gel?
Could you provide a formulation for a triple bleaching cream therapy containing hydrocortisone (or another low-potency corticosteroid), hydroquinone, and Retin-A, and how long would this cream remain stable?
Why is a high concentration of nipagine used in a cream containing 16 g cetyl alcohol, 20 g glycerin, 20 g olive oil, 0.5 g nipagine, 1 g sodium lauryl sulfate, and distilled water up to 100 ml, given that the usual concentration as a preservative is 0.1-0.2% of the water phase, and would it not be healthier to reduce this concentration or use aqua conservans instead?
What causes precipitation in a solution containing 0.1 g copper sulfate (CuSO4), 0.1 g zinc sulfate (ZnSO4), 1 g sodium borate, and 1 g boric acid in 100 ml of water when the sulfates and the borates are first dissolved separately and then combined?
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