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De helpdesk bevat meer dan 1500 vragen en antwoorden over diverse galenische topics, allemaal aangeleverd door Prof. R. Kinget.
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2468 resultaten gevonden
Is it possible to prepare a syrup with methionine as the active ingredient, and if so, how can optimal stability be guaranteed?
How can a correct base be obtained for making certain suppositories that require Witepsol E85 or Novata D suppository mass (melting point between 40-44°C), given that these masses are no longer in stock?
How can menthol be kept in solution for a preparation containing 5.925 g boric acid powder, 2.275 g menthol, 1 g borax, 0.2 g sodium lauryl sulfate, 35.71 ml isopropanol, 35.71 ml propylene glycol, and distilled water up to 250 ml, given that the solution remains clear until 150 ml but becomes slightly cloudy upon further addition of water?
How can a stable and homogeneous solution or suspension of 40,000 or 50,000 IU/ml be prepared for cystic fibrosis patients using vitamin A acetate 1,500,000 IU/g diluted in Miglyol oil, and what are the recommended shelf life and storage conditions, such as refrigeration, for this preparation?
How long is an opened container of retinol stable without inert gas, given that the packaging for water-soluble retinol and retinol acetate specifies using it as soon as possible after opening or storing unused portions under inert gas, and how can this be practically resolved?
Procal co (25 mg sodium fluoride) is no longer commercially available, and a request has been made for a magistral preparation for the treatment of otosclerosis; since Micromedex indicates that sodium fluoride converts into hydrofluoric acid, causing severe gastrointestinal side effects, would enterically coating the sodium fluoride capsules eliminate this phenomenon, or is such a preparation considered irresponsible?
Is there a formula for preparing ibuprofen suppositories, are they stable, and could an alternative syrup with a better flavor be suggested for a 2-year-old child who refuses to take Junifen syrup?
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