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De helpdesk bevat meer dan 1500 vragen en antwoorden over diverse galenische topics, allemaal aangeleverd door Prof. R. Kinget.
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How can the active ingredients diflucortolone valerate 0.6%, chloramphenicol 4 g, urea 10 g, and salicylic acid 3 g be incorporated into a 100 g hydrophobic ointment, and should vaseline or a mixture of white vaseline and liquid paraffin (70/30) be used as the hydrophobic base?
Do you have a formula for the preparation of a nitrofurantoin suspension for pediatric use (a generic alternative to Furadantine Pediatrie)?
What are the potential issues regarding acidity in a preparation containing 0.5 g salicylic acid, 1.5 g boric acid, 1 g erythromycin base, and vaseline up to 50 g, and is a 10% erythromycin overdose required to compensate for degradation loss, similar to the erythromycin and metronidazole preparation on page 315 of the Therapeutic Magistral Formulary?
Are there any incompatibilities in the following preparation: 3 g hydroxypropyl methylcellulose 6000, 6 g glycerine, 250 mg diphenhydramine HCl, 2 g lidocaine HCl, 100 ml suspension of magnesium trisilicate and calcium carbonate NF VI, 130 g sugar syrup, and water up to 300 ml, to be made into a mouthwash?
Regarding the TMF preparations of povidone-iodine 10g, macrogol 400 55g, macrogol 4000 25g, and purified water qs ad 100g, why is the use of aqua conservans prohibited, and would its use extend the shelf life beyond 2 months; furthermore, for a preparation of chlorhexidine acetate 1g and aqua conservans ad 100g, is the requirement for the patient to perform their own dilution due to limited stability, and what is the specific purpose of adding sodium chloride as seen in the specialty product Cedium?
How can a compounded preparation consisting of 40% metronidazole in a Beeler base up to 100 g be made for use in treating ulcers, how should it be processed, and is this formulation feasible given its reported use at UZ Gent?
What is the best way to prepare suppositories containing 25 mg belladonna extract, 100 mg butalbital, 100 mg caffeine, and 2 mg ergotamine tartrate using adeps solidus as a base, and is it necessary to include tartaric acid in this formulation as suggested by literature for ergotamine suppositories?
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