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De helpdesk bevat meer dan 1500 vragen en antwoorden over diverse galenische topics, allemaal aangeleverd door Prof. R. Kinget.
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2468 resultaten gevonden
Is chlorhexidine digluconate compatible with a Lanette wax cream containing 0.5g chlorhexidine digluconate and 0.05g vitamin A acid up to 100g, or should a different cream base be chosen, such as an unbuffered cetomacrogol cream without sorbic acid, given that Lanette N is anionic and incompatible? Additionally, should the final preparation be filled into a tube as per TMF or a plastic container according to other sources?
Can carbomer gel be used together with salicylic acid, specifically in a formulation of 3% salicylic acid in hydrophilic gel up to 100g, and considering that the gel became very liquid when rubbing the carbopol gel with salicylic acid but regained consistency after adding 3g of trometamol, is the salicylic acid still present in its acid form and, if not, is it still effective?
What is the recommended preparation method and which additives should be used for 20 adult suppositories containing 200 mg ichthammol, 1 mg prednisolone, 80 mg collargol, and 25 mg lidocaine, given that previous attempts using Novata B as a base, both with and without the addition of Aerosil, were unsuccessful?
Is it possible to provide a sterile 0.5% metronidazole solution in water for wound irrigation to replace the currently used Flagyl IV solution for a patient requiring large volumes for an extreme decubitus wound, and considering the availability of an autoclave and laminar air flow, what are the requirements regarding stability and buffering?
Is there a possibility to create a compounded preparation to replace Zalvor cream, which is used in hospitals during scabies epidemics but is a significant financial burden?
What cream base should be used to prepare a compounded preparation for Wartec cream containing 1.5 mg/g of podophyllotoxin in a 5 g tube, should the podophyllotoxin be dissolved in alcohol beforehand, or is it better to prepare a topical solution?
Can ephedrine base be replaced by ephedrine HCl in a classic nasal ointment containing 200 mg menthol, 200 mg eucalyptol, 500 mg borax, 150 mg ephedrine base, 5 drops of adrenaline 1/1000, 5 g paraffin, and 5 g almond oil, given that the base is no longer available for purchase in Belgium?
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