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De helpdesk bevat meer dan 1500 vragen en antwoorden over diverse galenische topics, allemaal aangeleverd door Prof. R. Kinget.
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Since Geomycine cream is no longer available and a doctor has prescribed it at 0.1% for an elderly woman's leg wound, is there a substitute available, and is it feasible to prepare a 0.1% gel using 80mg/80ml gentamicin vials? If so, can this be prepared with carbomer, methylcellulose (MC), or hydroxypropyl cellulose (HPC), what other excipients should be considered, and is disinfecting a mortar and pestle with rubbing alcohol sufficient to ensure the preparation is as germ-free as possible?
How should one begin preparing a formula prescribed by a physician containing 0.1g triamcinolone acetonide, 1g chlorhexidine diacetate, 3g lidocaine HCl, 10g propylene glycol, and 50g Cetomacrogol 1000 with water up to 100g, given that the resulting 50% Cetomacrogol 1000 base is extremely thick, solid, and barely spreadable?
What is the preferred preparation for a prescription of 100 ml tetracycline 5% intended to treat mouth ulcers, given that tragacanth is unavailable?
What is the explanation for the preparation failure and the resulting watery mixture, which is unsuitable for dispensing, when mixing the water and oil phases at 70°C for a formulation containing 20 g aluminum chloride, 20 g glyceryl monostearate, 2.5 g spermaceti, 2.5 g liquid paraffin, and aqua conservans up to 100 g?
Can a 2% minoxidil solution be formulated to reduce the strong smell of isopropyl alcohol, as a patient is complaining that the scent lingers in their hair, and is there a specific method or composition to make the odor less intense?
What causes precipitation in an alcohol-free mouthwash consisting of 6.0 ml chlorhexidine gluconate 20%, 0.17 g saccharin sodium, 1.0 g cetomacrogol, 30.0 g peppermint spirit, and purified water up to 1000 ml?
What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?
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