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De helpdesk bevat meer dan 1500 vragen en antwoorden over diverse galenische topics, allemaal aangeleverd door Prof. R. Kinget.
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What is the best way to prepare the carbocysteine syrup from NF 6, given that the carbocysteine does not fully dissolve when added to a solution of sodium bicarbonate (NaHCO3) in water?
What is the ideal way to reformulate a solution containing 5 ml (6.05 g) of lactic acid dissolved in 40 ml of water, 35 ml of ethanol, and 20 ml of propyleenglycol—which has been effective for a patient with ichthyosis for years—into a less liquid form such as a milk, gel, or emulsion while maintaining the same properties?
Given that PubChem indicates codeine should be protected from light under certain conditions and most specialty products containing codeine use red-brown containers, should compounded preparations based on codeine, such as the old Actifed formula, ideally be stored in a brown bottle?
Are antioxidants necessary when preparing chlorpromazine suppositories?
Given that Cefadroxil/Duracef syrup is unavailable, is a compounded alternative possible, considering the original syrup contains sodium benzoate, xanthan gum, titanium dioxide, polysorbate 40, sucrose, and various flavorings (lemon, raspberry, strawberry, and refreshing flavor)?
What is the correct preparation method for 10 urethral sticks for a 4-year-old girl, based on a formula containing 0.2% furacine, 2% procaine HCl, 43% PEG 1500, 47% PEG 400, and 7.8% water?
What is the best way to prepare a 100g cold cream formulation containing 5% urea, given that the preparation methods according to the Belgian Pharmacopoeia V and the USP (with borax) do not yield satisfactory results?
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