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De helpdesk bevat meer dan 1500 vragen en antwoorden over diverse galenische topics, allemaal aangeleverd door Prof. R. Kinget.
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2468 resultaten gevonden
How can a solution for external use be prepared containing 64 mg betamethasone dipropionate, 0.3 g Carbopol, 1.5 ml NaOH, 150 mg Na EDTA, 2% miconazole, 28 g isopropanol, and purified water up to 100 ml?
What does the term hydrophobic base gel mean in the context of a prescription for a hydrophobic gel containing a very high concentration of local anesthetics (23 g lidocaine, 3.5 g tetracaine, and 3.5 g tetracaine hydrochloride, with hydrophobic base gel up to 100 g) intended for skin numbing, considering that tetracaine is apparently only available as HCl in Belgium?
Can metronidazole 500 mg suppositories be used as an alternative to oral administration, and is it possible to use Suppocire AS2X as a base given that NF6 suggests Witepsol H15 with a displacement factor of 0.44 (not found in other lists), while Professor Remon recommends PEG-based suppositories for higher bioavailability?
How can I prepare hydrocortisone 1% ear drops for the middle ear, and can this be achieved by mixing the acetate form with a water solution containing a few drops of Tween?
How can a 20% benzocaine preparation in 200 ml be formulated for local anesthesia in a dental practice given that benzocaine is insoluble in water, the salt form is unavailable, and the dentist requires a sweet taste—possibly through the addition of sugar—without having specified the solvent?
How can the stability issue of a W/O cream containing 9 g lactic acid, 30 g paraffin, and vaseline cum aqua with arlacel up to 300 g be resolved, given that the emulsion currently breaks?
What causes inconsistent crystallization in a phosphate syrup containing 73g sodium monohydrogen phosphate, 17.5g potassium dihydrogen phosphate, 150ml Syrupus simplex, 6ml raspberry aroma, and water up to 300ml, prepared by dissolving powders in a mixture of 150ml syrup and 60ml water heated to 60°C, and how can this be prevented given that it is a supersaturated solution (solubility 1 in 8) and the patient claims to store it correctly and shake it well?
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