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De helpdesk bevat meer dan 1500 vragen en antwoorden over diverse galenische topics, allemaal aangeleverd door Prof. R. Kinget.
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2468 resultaten gevonden
What is the protocol for preparing a Mifegyne suspension for a patient with swallowing difficulties, considering it must be crushed in a biohazard cabinet and ingested under physician supervision, and given its poor water solubility, would delivering it as a suspension be a viable option to ensure staff safety and ease of intake despite a lack of available data?
Are creams containing a combination of chlorhexidine and zinc oxide compatible or incompatible, given that Martindale states chlorhexidine is incompatible with anionic components and its activity decreases in the presence of cations like Zn2+, and what is the correct formulation approach considering that while no visible incompatibilities occur in cetomacrogol cream due to opposing charges, it has been suggested to omit chlorhexidine despite dermatologists not supporting this recommendation?
What is the recommended method to achieve a complete solution for a preparation of 2% w/v iodine in 98% w/v almond oil, given that the iodine does not fully dissolve and leaves a residue at the bottom of the measuring beaker?
How can 10% saponin be incorporated into hydrated petrolatum, given that using 10% Arlacel only keeps the mixture stable for an hour before the saponin separates?
When Jaborandi tincture is added to an aqueous solution of 250 mg pilocarpine HCl, 2 g Jaborandi tincture, 6.7 g alcohol 95°, and 10 ml distilled water (dosage: 3 x 8 drops per day), a precipitate forms; is this caused by the precipitation of alkaloids or the presence of essential oil, and would the preparation still achieve its intended effect for an elderly patient suffering from excessive salivation?
Should lidocaine base or lidocaine HCl be used in suppositories, and is lidocaine as effective as lidocaine HCl in this formulation?
What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?
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