Regarding the TMF nitrofurantoin suspension, which specific adverse effects result from breaking macrocrystalline agglomerates through excessive mixing, and since particle size affects bioavailability, wouldn't thorough distribution actually improve homogeneity and dosing accuracy? Does glycerol serve as a wetting agent for the particles, could xanthan gum be used as an alternative to Avicel (and if so, what is the recommended formulation), and would adding 0.5 to 1 mg/ml of sucralose be a useful sweetener?

How can the stability and consistency of a non-ionic hydrophilic cream (FN V)—composed of 15 g cetomacrogol emulsifying wax, 10 g liquid paraffin, 10 g propylene glycol, 0.2 g sorbic acid, and 64.8 g water—be maintained when the standard preparation method from the Memento of Galenic Pharmacy results in a liquid consistency that further thins upon the addition of 10,000 IU nystatin, 0.1% triamcinolone acetonide, 10% zinc oxide, and 0.5% chlorhexidine diacetate?

What is the cause of the hydroxypropylcellulose polymer precipitating and clumping after adding 125 g of sorbitol to a stomatitis cocktail containing 200 mg lidocaine HCl, 400 mg prednisolone, 3 million units nystatin, 5 g hydroxypropylcellulose, 10 ml propylene glycol, and water up to 500 g, even though a translucent, homogeneous gel was initially obtained by swelling the polymer in water after moistening it with propylene glycol?

Is it possible to make a stable preparation of minoxidil 5% in Cutivate cream?

Can mannitol be used as a filler instead of glucose for preparations used in neonatology, specifically for preparations with vitamin C, vitamin E, and folic acid, or is it better to consider mannitol with silicon dioxide as the standard filler for capsules?

Is 2% propranolol in buffered cetomacrogol cream stable for the treatment of hemangioma in a 2-month-old baby?

What is a pasta that can be applied to a stoma?