Regarding a 5% cocaine solution for an ENT specialist consisting of 5 grams of cocaine HCl, 20 drops of 0.1% adrenaline, and water up to 100 grams, should sodium metabisulfite or EDTA be used to stabilize the adrenaline and in what quantity, can aqua conservans be used as a preservative, how long can the preparation be stored, and must the final solution be isotonic?

Is it possible to prepare a dermaticum containing 10% magnesium sulfate?

What is the best way to prepare suppositories containing 900 mg potassium bitartrate, 600 mg sodium bicarbonate, and 1.2 mg sodium picosulfate, given that using 3 ml of Laxoberon as the source of sodium picosulfate consistently results in a curdled mass, and should an additional substance be added to prevent this or should the product be replaced?

Cremor hydrosorbatis 33 is no longer reimbursed; what is the best replacement for this to ensure the preparation is reimbursed?

What is the cause of the small lumps and potential incompatibility in a cream containing 5 g salicylic acid, 0.1 g triamcinolone, 3 g liquor carbonis detergens, 5 g Tween 60, 7.821 g Lanette N, 13.035 g vaseline, 5.214 g paraffin, and 60.83 g water, given that while salicylic acid and saponins in coal tar decrease emulsion stability, the issue appears to be a formula incompatibility rather than general instability?

What is the specific formula containing a certain percentage of phenol that can be used to treat remnants of ingrown and largely removed toenails, as requested by a doctor?

What is the most suitable excipient for a cream containing 10 kE bacitracin, 250 mg neomycin sulfate, and 100 mg prednisolone per 50 g, given that neomycin sulfate is incompatible with Beeler base and its efficacy is affected by Tween 80, while bacitracin activity decreases in combination with macrogol; and considering the formula for Nebacetine ointment (liquid paraffin, cetyl alcohol, lanolin, white petrolatum, and PEG-20 glyceryl oleate) as a potential base, are there any pharmacy-accessible alternatives to PEG-20 glyceryl oleate?