Should metronidazole be prepared in a non-ionic hydrophilic cream or in an anionic hydrophilic cream?

What are the recommended formulations for miconazole and itraconazole eye drops, given that a patient with fungal keratitis treated with itraconazole eye drops developed a persistent white coating on the cornea likely due to solubility issues, and considering that such preparations are difficult to obtain in the Netherlands if not listed in an official compendium?

Why is CaCO3 combined with DHEA?

Can menthol be incorporated into cold cream, and if so, up to what concentration can it be processed without causing stability issues?

What is the ideal preparation method and suppository base for a prescription of 65 mg Na EDTA per suppository, given that the dose is 1 mg per kg of body weight to be used once a week, and considering the lack of information regarding the heat sensitivity of Na EDTA and the accuracy of this dosage?

Is a pH adjustment required for metronidazole in the following prescription: 0.75% metronidazole, 5% propylene glycol, 0.1% Na EDTA, 0.25% trometamol, 0.5% polyacrylic acid, 0.08% methyl 4-hydroxybenzoate, 0.03% propyl 4-hydroxybenzoate, and purified water up to 60g?

What can a prescription for Amphocerine K, which is no longer available, be replaced with?