How should I prepare 10% methyl salicylate in carbopol gel up to 100g, given that while a clear gel is obtained during processing, methyl salicylate and/or water subsequently leak from the gel?

What is the best way to prepare a prescription for a 2% miconazole nitrate cetomacrogol emulsion (TMF), specifically regarding the buffers, given that the specified buffers are unavailable and could an alternative be used, the buffers be omitted, or a cetomacrogol lotion (memento) be made instead, or is miconazole nitrate only active at pH 5?

What composition can I use for a vaginal cream with prasterone (DHEA) 2.5% in carbomer gel?

Is it possible to prepare rectioles using Depakine solution for a palliative ZNA patient who cannot swallow, given that the current preparation starting from Depakine E.C. is intensive and potentially inaccurate, the active raw material is unavailable, and the formula suggested by Sanofi (1.04 g Depakine solution with 2.5 g Novata E instead of Novata B) cannot be used because that mass is also no longer available?

What is the use of the following oil containing 1g saponine coal tar, 25ml Dehydol 50, 35ml Cetiol V, 50ml Emulgin O 5, 50ml sweet almond oil, 40g Comperlan KD, and liquid paraffin up to 500ml (to be applied once in the evening), and how can a water-washable alternative be formulated using available raw materials and considering reimbursement, given that Dehydol is unknown?

How should a preparation for a cystic fibrosis patient containing 100 IU cholecalciferol, 100 mg alpha-tocopherol succinate, and 1 mg menadione sodium bisulfite per capsule for 60 capsules be formulated, and what is the best method for diluting cholecalciferol with lactose or mannitol given that 1 mg equals 40,000 IU, assuming there are no interactions between the products?

Given that Colitofalk is unavailable until May 2022, what special precautions should be taken when compounding mesalazine suppositories magistrally?