What is the recommended procedure to prevent the formation of a white, flake-like precipitate in a preparation containing 1% estradiol valerate and 1.5% sodium lauryl sulfate in antiseptic alcohol up to 100%, and would substituting the antiseptic alcohol with methanol improve solubility as suggested by Martindale?

Regarding the formula for diazepam rectal tubes containing 10 mg diazepam, 2.4 mg benzoic acid, 0.9 cc propylene glycol, 0.3 cc ethanol 94, 100 mg sodium benzoate, and purified water up to 2 cc, is there a specific reason why sodium benzoate is used as a preservative instead of aqua conservans?

What is the recommended solution for a preparation containing 7% salicylic acid, 0.05% betamethasone dipropionate, and 5% liquor carbonis detergens (LCD) in cetyl ointment with water up to 100%, given that the ointment breaks even after adding Tween 80 or substituting the base with 10 g Arlacel and anhydrous vacuum absorption (AVA) cream?

What is the best way to prepare a formulation containing 150 g Ichthammol, 150 g Tween 20, 2 g carboxymethylcellulose, and water up to 1 l, with instructions to use 2 tablespoons per bath, and is there an incompatibility between Ichthammol and carboxymethylcellulose?

Is it possible to obtain a stable gel with erythromycin, prednisolone, and Carbopol gel TMF, considering that the gel does not break but white flakes remain after extensive rubbing and the consistency of the final product is quite grainy?

The following lotion appears to be quite unstable: 21g urea, 30g liquid paraffin, 30g yellow petrolatum, 15g sorbitol, 15g glycerin, 9g adeps lanae, 3g stearic acid, 3g cetyl alcohol, and preserved water up to 300g; once cooled, the milk begins to separate every time. Can an emulsifier be added, considering this formula has been successful in the past?

How can the sedimentation of a preparation containing 1700 mg of chloramphenicol and water up to 100 ml, intended for a child with suspected meningitis, be prevented after an unsuccessful attempt to suspend the chloramphenicol using xanthan gum?