How should a 25mg/5ml trazodone oral suspension be prepared given the lack of literature, and specifically, should it be formulated as an acidic suspension using a citrate buffer as seen in a Michigan pharmacopeia formula with cherry syrup, or is using simple syrup acceptable as advised by APB documentation?

How can we resolve issues with preparing 28 ovules containing 500 mg of boric acid using a gelatin base, given that both hydrous and anhydrous glycerogelatin result in soft ovules that stick to each other, fingers, and the mold (even when lubricated with glycerol), making them difficult to insert, and would using liquid paraffin as a lubricant be a better alternative?

Regarding a rectal ointment composed of 1.5g bismuth subnitrate (basic), 1.2g zinc oxide, 0.4g menthol, 0.45g adrenaline HCl 1:1000, 450mg cocaine HCl, and 18g each of lanolin and vaseline to be applied locally three times daily: can bismuth subnitrate be used if only that is available from the wholesaler; what alternative can be used for adrenaline HCl since it is no longer on the market; are there any specific instructions for the overall preparation method; and is reimbursement possible, potentially with an adjustment to the prescription?

In a solution containing 1g boric acid, 1g sodium borate, 100mg copper sulfate, and 100mg zinc sulfate in water up to 100g for use as compresses, a precipitate forms when the copper and zinc sulfates are added to the dissolved boric acid and sodium borate; could this be due to the environment being too acidic?

How should Losec be formulated for administration to children?

Can you explain the discrepancy in the calculated weights for the preparation of 50g of benzoyl peroxide and erythromycine TMF ointment, given that a 10% excess is required for product instability, benzoyl peroxide has a 25% water content, and an additional 10% of all ingredients must be added to account for loss in the ointment mill, resulting in TMF/instructor values of 1.98g for erythromycine and 4.03g for benzoyl peroxide while my calculations were 1.815g and 3.66g respectively?

What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?