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The compounding helpdesk contains more than 1500 questions and answers on various galenic topics, all provided by Prof. R. Kinget.
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Which excipient is best used for the following preparations for a premature infant: folic acid, vitamin C, and alpha-tocopherol acetate (each separately), considering that while mannitol is recommended for folic acid and dried starch is suggested for vitamin C, an alternative excipient might be better suited for a premature infant?
What is the shelf life and stability of a prescribed oral suspension containing 1 mg/10 ml budesonide in xanthan gum for the treatment of esophageal inflammation, where the patient takes 10 ml twice daily, and are any extra excipients required for this formulation?
How can the very bitter taste of a syrup based on proguanil (Paludrine 500 mg per 100 ml) be masked as much as possible?
What is the formula for diltiazem suppositories, given that while nifedipine was previously used in ointments and suppositories, diltiazem HCl is now also used for treating fissures; additionally, what would be an appropriate dose for these suppositories, and should there be concerns regarding arrhythmogenic properties since the hepatic first-pass effect is bypassed?
Given that the water-soluble vitamin A solution is unavailable, is it possible to prepare an oral liquid with a concentration of 50,000 I.U. / ml?
Should we use buffered or unbuffered cetomacrogol cream TMF for 1.5 g of tetracycline HCl in cetomacrogol cream TMF?
What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?
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