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The compounding helpdesk contains more than 1500 questions and answers on various galenic topics, all provided by Prof. R. Kinget.
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What is the explanation and solution for the formation of large clumps and a sticky mass when preparing a cream containing 2% levomenthol and 4% erythromycin in 100 grams of cetomacrogol cream, specifically considering that the menthol was first dissolved in ether, mixed with a small amount of the cream, followed by the geometric addition of erythromycin and the remaining cream, and processed using a sample mill?
What is the appropriate preparation method for a complex oncological wound ointment consisting of 25 g Vioform, 150 g zinc oxide, 125 g olive oil, 50 ml Linisol 2%, 25 ml Exacyl ampoules, 25 g Orahesive powder, and white petrolatum up to 500 g (with the potential addition of one box of Flagyl 500 metronidazole upon a doctor's request), specifically regarding the proposed approach of mixing the aqueous solutions (Linisol and Exacyl) with zinc oxide before adding olive oil and then blending Vioform with Orahesive powder in a mortar before adding the petrolatum, and are there any known long-term interactions or specific shelf-life considerations for this preparation?
What is the composition of Lanette wax milk used in the following lotion, and what is the best method to prepare this lotion containing 8% salicylic acid and 0.05% clobetasol propionate in Lanette wax milk ad 100%?
How can a 2.5% sodium hypochlorite solution be prepared at the request of a dentist, given that Febelco only stocks 10-15% active chlorine sodium hypochlorite from the company Acros?
For a 3 mg/ml acetylsalicylic acid syrup requested by a veterinarian, should vitamin C be added, which syrup is best to use (plain sugar syrup, raspberry, or banana), and what is the stability?
What is the best method to prepare a mouthwash containing 0.6 g lidocaine HCl, 50000 IU/g vitamin A oil solution, 1.5 g hydrocortisone acetate, 5 g hydroxyethylcellulose, 90 ml simple syrup, and peppermint water up to 300 g, given that solubilization of the vitamin A solution with Tween 80 is required and 10 g of a 1,500,000 IU/g vitamin A acetate oil solution is available; specifically, how much Tween 80 should be used, are adjustments to other substances necessary, and is the taste acceptable or should sodium saccharin be added?
How can a potassium permanganate solution be thickened for easier application given that a 1% Klucel mixture changed from purple to dark reddish-brown after two hours, and what is the chemical reaction occurring or which alternative viscosity enhancer should be used?
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