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The compounding helpdesk contains more than 1500 questions and answers on various galenic topics, all provided by Prof. R. Kinget.
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What is the function of glycerin in the original formula containing 400 mg codeine phosphate, 80 mg triprolidine HCl, 1200 mg pseudoephedrine, 4 g guaifenesin, 5% glycerin, and simple syrup up to 200 ml, and should the glycerin still be included if the simple syrup is replaced by 100 ml of 70% sorbitol syrup and water up to 200 ml for a diabetic patient?
What is the maximum dose of DHEA or prasterone, given that I have a prescription for capsules containing 50 mg of prasterone to be taken once daily, but no dosage guidelines can be found in any reference books?
What is the correct preparation method for an oral gel containing nystatin?
What is the procedure for preparing a 1% sildenafil gel or cream, as requested by a physician for sildenafil or tadalafil?
Does a formula exist for suppositories containing erythromycin (succinate or propionate), and is there rectal absorption?
Is there an alternative to aluminum chloride as an antiperspirant?
How can an unstable vaginal cream containing 3 g sulfacetamide, 3.5 g sulfathiazole, 2 million IU nystatin, 0.2 mg ethinyl estradiol, 4 g glycerol monostearate, 14 g liquid paraffin, 15.5 g white petrolatum, 7.5 g cetomacrogol, 10 g propylene glycol, and water up to 100 g be successfully formulated, given that the base consistently breaks and remains liquid even after increasing the amounts of petrolatum and cetomacrogol, and is it permissible to use polysorbate in a vaginal cream since its addition provided a noticeable improvement in stability despite the active ingredients making the mixture appear even more unstable?
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