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The compounding helpdesk contains more than 1500 questions and answers on various galenic topics, all provided by Prof. R. Kinget.
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How can a stable emulsion be prepared with the following composition: 7.5 g menthol, 7.5 g chlorobutol, 90 g hamamelis water, 90 g antiseptic alcohol, 24 g perhydrosqualene, and 9 g polysorbate 80, given that a previous attempt using Lanette SX as an emulsifier was not stable?
How can a patient be treated with an aerosol solution comparable to PULMICORT suspension for nebulization 2 ml, but with beclomethasone dipropionate 250 micrograms per 1 to 2 ml as the active ingredient?
What is the best method to prepare an oil-containing non-ionic ointment consisting of 2.5 g hydroquinone, 50 mg triamcinolone acetonide, 25 mg tretinoin, 500 mg lactic acid, 5 g glycerin, 500 mg ascorbic acid, 75 mg sodium edetate, 3 g white wax, 2.5 g cetaceum, 15.5 g Cetiol V, 1 g Span 80, 4 g sorbitan sesquioleate, and aqua conservans up to 50 g, given that the ointment currently breaks during preparation?
What is the recommended preparation method to prevent crystal formation in a 10% gabapentin and 0.5% doxepine formulation in unbuffered cetomacrogol cream, given that an 8% gabapentin version was stable but the 10% version crystallized within hours even after adjusting the pH to 7.3?
Which cream base is best used to recreate Eoline cream?
What are the tips for preparing a loco Peridontone formulation consisting of 9.6 g framycetin sulfate (to be replaced by neomycin sulfate), 15 g papain 150 FIPU, 8 g sodium benzoate, and methylcellulose (MC) mucilage up to 100 g, given that the gel, intended for interdental injection, becomes liquid after adding all components even when using 3% methylcellulose 400 cps, suggesting an interaction that breaks down the gel?
What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?
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