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The compounding helpdesk contains more than 1500 questions and answers on various galenic topics, all provided by Prof. R. Kinget.
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What would be the best suspending agent, such as Veegum, for a preparation containing 2 g each of salicylic acid, prednisolone, chloramphenicol, and zinc undecylenate, along with 20 g of alcohol, 6 g of propylene glycol, and water up to 100 ml?
What is the best way to resolve the issues with a suspension containing 8 g disulfiram, 10 g acacia gum, 5 g glycerol, 120 mL water, 6 g anise spirit, and syrupus simplex up to 300 mL, given that the mixture is flaking and the components are floating on top?
How can I prepare a stable 1% indomethacin gel that does not discolor, and should I adjust the pH or is the issue located elsewhere?
How can methoxsalen suppositories be compounded from Oxsoralen capsules, according to a request received by a pharmacy intern at the drug information center in West Palm Beach, Florida, from a pharmacist in Ponce, Puerto Rico?
A dermatologist from our hospital prescribes 2% erythromycin in cetomacrogol cream up to 100 g, buffered with a borate buffer to pH 8.6; however, can buffered cetomacrogol cream be used instead, given that erythromycin is most stable at pH 6?
What formula can be used to incorporate 1 to 3% phenytoin into a local ointment for the treatment of atone wounds, as referenced in the study by Rhodes RS, Wilson SE, and Phatak HM titled Topical phenytoin treatment of stage II decubitus ulcers in the elderly published in Ann Pharmacother 2001; 35(6):675-681?
Are these nasal drops isotonic, given the formula containing 2.5 g phenylephrine HCl, 1.0 g naphazoline HCl, 5.0 g chlorobutanol, 200 mg menthol, 5 drops of eucalyptol, 20 ml glycerine, 10 drops of Tween 80, and 20 ml propylene glycol, with water added to 1 l?
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