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The compounding helpdesk contains more than 1500 questions and answers on various galenic topics, all provided by Prof. R. Kinget.
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What is the best way to prepare a ketamine 5% cream for the indication of neuropathic pain, given that ketamine is also used abroad for this indication in a 10% concentration?
What is the rate of decomposition (in hours, days, etc.) of hydrogen peroxide when used for the disinfection of face masks?
What is an alternative for Trianal suppositories containing lidocaine HCl and triamcinolone acetonide, given that the available suppository bases are Suppocire AS2X, Novata B, and Witepsol?
How should suppositories with 150 mg of collargol be prepared in a 2 g mold instead of the 3 g mold specified in the TMF, and should the 150 mg dose be reduced to 100 mg (150/3 x 2) for the 2 g mold, especially since prescriptions often specify a percentage where the amount of collargol depends on the mold size, such as 5% resulting in 100 mg for a 2 g suppository and 150 mg for a 3 g suppository?
What would be the best base for incorporating permethrine to treat scabies, specifically one that is liquid enough to be effectively massaged into skin folds?
What is the reason for the clumping observed in a preparation containing 2 g each of flufenamic acid and lidocaine base in 100 g of cetomacrogol cream TMF?
How can 25 g of saponinated coal tar be effectively incorporated into a formulation containing 20 g of Elocom lipophilic cream 1 mg/g and Beeler basis up to 100 g, given that previous attempts—including evaporating the saponinated coal tar onto starch—have failed to produce a good result despite the unusually high percentage of coal tar?
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