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The compounding helpdesk contains more than 1500 questions and answers on various galenic topics, all provided by Prof. R. Kinget.
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What is a possible solution for genital warts, specifically a blue solution used 20-30 years ago, that was requested by a doctor?
Does anyone have experience preparing Nembutal (pentobarbital) 30 mg and 60 mg suppositories for pediatric use, and could the choice between pentobarbital or sodium pentobarbital affect whether the substance dissolves completely into the suppository base, as it reportedly did in the past, rather than precipitating as small powder particles?
Is there a possible formula for preparing a paste used in the Payne technique for speech therapy, given that a local therapist has a sample from the Netherlands with a label only listing the composition as various types of toothpaste, pumice powder, essential oil, and fluorescein?
What is the best way to prepare an enema containing 3 mg beclomethasone dipropionate, 1 g 5-ASA, 0.3 ml 94% ethanol, 0.2 ml 15% methyl hydroxybenzoate in propylene glycol, and 25 g Carbopol water gel, with distilled water added to 60 ml, for a total volume of 600 ml?
What is the best way to prepare an ointment containing 30 ml of nitroglycerin 1% (w/v) alcoholic solution, 5 g of lactose, 10 g of liquid paraffin, and white vaseline up to 100 g, given that the amount of alcohol cannot be incorporated even with the addition of Tween 80 or Arlacel 83, and considering that a previous urgent delivery using eucerin and 3% Tween 80 was only partially successful due to alcohol evaporation; furthermore, would it be feasible to use 10 or 15 grams of lactose, allow the alcohol to evaporate by rubbing, and replace the lost volume with vaseline?
How can I prepare a solution containing 2% erythromycin base and 1% hydrocortisone acetate in 70% isopropanol up to 200 ml, given that precipitation occurs even after heating?
What is an effective and stable formulation for highly hypertonic 10% cocaine eye drops used for diagnosing Horner's syndrome, given that a previous 4% formulation buffered with boric acid/borax and preserved with hydroxybenzoates was found to have suboptimal tolerability?
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