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Die Rezeptur‑Helpdesk enthält mehr als 1500 Fragen und Antworten zu verschiedenen galenischen Themen, alle bereitgestellt von Prof. R. Kinget.
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How should a prescription for 60 capsules of 50,000 units of retinol per capsule (dosage: 1 capsule per day) be prepared using only the available 10% aquasolubile beta-carotene, and is this dose considered safe given that Prof. Merlevede's book suggests 5,000 to 30,000 IU daily for chronic deficiency or 200,000 IU once, while noting that toxicity symptoms from more than 50,000 IU per day in adults only appear after a long latency period?
Should a preparation containing 20 mg boldo extract, 5 mg belladonna extract, 0.3 mg ergotamine tartrate, and 30 mg caffeine per capsule, stored in a vial with a desiccant cap, be kept in the refrigerator or not?
How can the lactic acid be prevented from leaking out during the grinding and mixing of a preparation containing 5g salicylic acid, 4g lactic acid, and vaseline up to 15g?
Is carbopol gel a suitable base for a 0.5% morphine prescription, considering the potential impact of the gel's pH and anionic nature on the stability or incorporation of morphine?
How should the preparation of a 2.5% hypochlorite solution for a dentist be approached, given that concentrated hypochlorite solution is no longer commercially available, only technical-grade hypochlorite solution has been found (which seems inappropriate), and sodium hypochlorite powder can no longer be ordered via the Qualenica website?
Can a formula for a magistral preparation of Lacta-gynecogel be recommended, and is it permissible to dispense such a gel given that vaginal douches like Lactacyd are no longer allowed?
What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?
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