Is it possible to make an officinal preparation of Zinolium (ZnSO4 gel) using a formula containing 1.78g ZnSO4.7Aqua, 2g Carbopol 980, 50mg Na-EDTA, 15g propylene glycol, 4.058g trometamol, and aqua conservans ad 100g, given that water separates from the gel whenever the dissolved zinc sulfate is added to either a self-prepared or a prefabricated carbomer gel (TMF composition)? Does this problem stem from an incompatibility between zinc sulfate and Carbopol, or is it caused by replacing triethanolamine with trometamol for neutralization, and is there a viable Carbopol-based alternative to the methylcellulose composition in the NF?

How can a stable emulsion be prepared with Locoid Crelo and 3% salicylic acid, given that simply rubbing the salicylic acid into the emulsion previously resulted in instability and the formation of lumps after a few weeks?

How should 150 mg of chloral hydrate be processed in a PEG suppository base using only PEG 400 and PEG 4000, given that a 2:3 ratio yields a barely firm suppository while increasing PEG 400 results in insufficient hardness? If the current mixture has a melting point of 37-38°C and dissolves in 10 minutes at 37°C, can it be used for an epileptic seizure lasting only 5 minutes, and how can the melting point be lowered toward the ideal 35°C without adding more PEG 400?

Can chloramine be used for "cold" sterilization of materials, such as connectors for tube feeding?

What is the function of sodium monohydrogen phosphate dihydrate in the TMF oral gel with hydrocortisone acetate and lidocaine HCl, considering it is the only oral gel in the TMF that contains this substance?

What is the recommended preparation method for 20 suppositories containing 250 mg ichthammol, 80 mg papaverine HCl, and 20 mg belladonna dry extract, given that the ichthammol clumps together and the mass is no longer homogeneous during pouring, even after adding 2.5 g Arlacel C?

What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?