With which product can tragacanth be replaced in a prescription consisting of 25 mg prednisolone disodium sulfate, 12 drops of opium tincture, 0.8 g tragacanth, 12 g sulfaguanidine, 15 g 5-aminosalicylic acid, and water up to 300 cc, with instructions for a 40 ml enema in the evening?

What is the ideal preparation method for a solution containing 17.5 g salicylic acid, 5 g acetone, and ricinated collodion up to 50 ml, given that the salicylic acid is very difficult to dissolve and forms a thick paste after cooling if heat is used?

What is the best way to prepare a Lamictal syrup according to a prescription of 6 g Lamictal in syrupus simplex up to 150 ml, and is it acceptable to dispense a white syrup after "dissolving" 30 dispersible tablets of 200 mg in 40 ml of water, diluting it with syrupus simplex to 150 ml, and applying a "shake before use" label?

Why does Affusine, a cream containing fusidic acid, break after adding metronidazole to a prescription of hydrocortisone, metronidazole, and Affusine cream (containing fusidic acid, cetyl alcohol, glycerol, paraffin, polysorbate, HCl, and water), is there a pH problem between metronidazole and fusidic acid, and can this be easily resolved by adding an extra w/o emulsifier such as Arlacel?

Can sodium bicarbonate be added to a nasal ointment containing 200 mg eucalyptol, 300 mg ephedrine DL base (which may be replaced by ephedrine HCl), 5 drops of adrenaline tartrate ampoule (1 mg), 20 g white vaseline, and 10 g sweet almond oil, or should it be omitted—similar to borax—to prevent an alkaline environment that destabilizes adrenaline, and is the bicarbonate still necessary to neutralize the acidity of ephedrine HCl for the nasal mucosa; additionally, is white vaseline appropriate for a nasal ointment or is yellow vaseline preferred?

What is the necessary composition for a carbomer gel containing 1% clindamycin HCl and 0.1% triamcinolone acetonide to achieve the most stable preparation possible?

What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?