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Die Rezeptur‑Helpdesk enthält mehr als 1500 Fragen und Antworten zu verschiedenen galenischen Themen, alle bereitgestellt von Prof. R. Kinget.
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Can you provide the composition of glycopyrrolate or glycopyrronium oral solution FNA?
What is the cause of crystals forming in an ibuprofen gel composed of 88% aqua, 4.73% N-methylglucamine, 5% ibuprofen, 0.45% of a 25% HCl solution, 2% Natrosol, and a preservative, given that the product should be a clear gel with a pH between 6.8 and 7.2?
Is it problematic to add a sour raspberry flavor to a mouthwash containing hydrocortisone acetate, lidocaine base, nystatin, propylene glycol, HPMC, and water because a patient is complaining about the taste?
What is the cause of crystallization in a preparation containing 4 g minoxidil, 60 mg betamethasone valerate, 20 g propylene glycol, 30 g alcohol 60°, and water up to 200 ml, and what are the required amounts of alcohol or propylene glycol to prevent this, given that the components initially dissolve with heating but recrystallize after several hours?
Is it a standard rule to weigh 5% extra active ingredient when preparing capsules, given that in 2011 two preparations were only marginally compliant at 90.3% of the prescribed dose when 5% extra was added, but this practice has been discontinued leading to concerns about current compliance, especially since 10% extra is still weighed for folic acid?
What is a lotion or gel containing 20% diethyltoluamide?
What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?
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