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Die Rezeptur‑Helpdesk enthält mehr als 1500 Fragen und Antworten zu verschiedenen galenischen Themen, alle bereitgestellt von Prof. R. Kinget.
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Can anyone tell me how long phosphate syrup can be stored, as I cannot find any information regarding its stability?
How can liquid phytomenadione be incorporated into capsules containing alpha-tocopherol acetate 100 IU, cholecalciferol 1000 IU, menadione sodium bisulfite 2.5 mg, and retinol acetate 5000 IU for 60 capsules, considering that menadione sodium bisulfite is unavailable at the wholesaler?
Can you provide an explanation and the preparation method for a formula containing 500 mg chlorhexidine gluconate, 1 g lidocaine HCl, 9.7 g HPMC 4000, 1 g raspberry extract, and white vaseline up to 50 g, intended for application to the tongue?
What is the recommended method for preparing 100 g of a liposomal cream containing 10% testosterone propionate?
Which products can be used to replace Tensomel and Tensagex in the preparation of a shampoo containing 15 g lactic acid, 5 g salicylic acid, 5 g borax, 12 g Tensomel, 200 g Tensagex, and purified water up to 400 g, given that these two surfactants are no longer available?
How can a stable preparation be achieved for a mouthwash containing 125 mg clobetasol propionate, 202 mg nystatin powder (half a bottle), 400 mg lidocaine HCl, 10 ml propylene glycol, and water up to 250 ml, given that precipitation occurs as soon as water is added to the mixture of clobetasol propionate and propylene glycol?
Is it necessary to add alpha-tocopherol as an antioxidant to a vitamin K1 solution in peanut oil, and if so, what is the recommended concentration? Additionally, would it be useful to add a preservative, or is this unnecessary, and if useful, what would you suggest?
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