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Die Rezeptur‑Helpdesk enthält mehr als 1500 Fragen und Antworten zu verschiedenen galenischen Themen, alle bereitgestellt von Prof. R. Kinget.
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How can an oral viscous budesonide (Pulmicort) suspension (solution) be prepared for the treatment of a patient with (eosinophilic) esophagitis?
What is the best way to prepare sterile ear drops containing 200 mg miconazole nitrate, 50 mg chloramphenicol, 100 mg hydrocortisone acetate, 150 mg boric acid, 30 mg borax, 70 mg sodium chloride, 3 drops of polysorbate, and water up to a total of 10 g?
Is it possible to formulate nitrofurantoin as a 20 mg suppository for a baby who needs to take it preventatively for one year but has issues with oral administration, and is there sufficient rectal absorption to consider this route or would a dose adjustment be required due to inadequate absorption?
What could be the cause of a cream containing 0.025 g betamethasone dipropionate (used as 250 mg of a 10% trituration in mannitol), 2.5 g salicylic acid, 2.5 g Tween 80, and buffered cetomacrogol cream up to 50 g breaking or decomposing after approximately 3 weeks, given that extra fine salicylic acid and a 10% trituration from Fagron were used?
Regarding a prescription for 60 compounded capsules of Cymbalta 20mg (duloxetine), where the original specialty consists of capsules filled with enteric-coated pellets, can these pellets simply be processed into new capsules or must the final capsules themselves be enteric-coated, considering the lack of available data on the stability of duloxetine?
How can a water-soluble vitamin A solution be incorporated into a nasal ointment containing 20 g white vaseline, 10 g liquid paraffin, 0.5 g menthol, and 5 ml water-soluble vitamin A palmitate 1000, and specifically, what amount of vitamin A did the prescriber intend for this old NKO Leuven formula, given that the preparation was adapted based on Vitapanthol nasal ointment levels after consulting with the GHB pharmacy and the BAF?
What is the expiration date of a cream containing tretinoin, both at room temperature and when refrigerated?
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