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Die Rezeptur‑Helpdesk enthält mehr als 1500 Fragen und Antworten zu verschiedenen galenischen Themen, alle bereitgestellt von Prof. R. Kinget.
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What is the correct procedure for preparing 30 mg duloxetine capsules, specifically regarding whether the granules found in Cymbalta capsules can be crushed before enteric coating, or if they should instead be mixed with lactose for even distribution without crushing, and is an additional enteric coating still required if the granules remain intact?
How should a syrup containing prednisolone disodium phosphate be prepared using SyrSpend at a pH of 4?
What is the maximum dose for a Lugol's solution (5g iodine, 10g potassium iodide, water up to 100ml) for thyroid disorders, given that the usual dose of 3x10 drops per day equals 75mg of iodine (based on 1 drop = 0.05ml), which exceeds the maximum daily dose of 60mg?
What is the formula for a magistral preparation of progesterone (200 mg) ovules as an alternative to the unavailable Utrogestan vaginal capsules?
How can Cliptol gel be prepared, given that it is a French specialty product with a composition per 100g of 5g ibuprofen and 3g levomenthol, and contains carbomer 980, diisopropanolamine, purified water, ethanol 96%, and propylene glycol as excipients?
What is the best base to incorporate 5% acyclovir for a 10 g lipophilic cream for herpes labialis to ensure a stable preparation that remains as transparent as possible upon application?
Can light magnesium subcarbonate be replaced by the heavy variant in a magistral syrup preparation prescribed by an internal medicine specialist containing 31g citric acid, 18g magnesium subcarbonate, 202g water, and 47g simple syrup with preservative, given that the light variant is no longer available and there is no information regarding the dosage or indication?
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