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Die Rezeptur‑Helpdesk enthält mehr als 1500 Fragen und Antworten zu verschiedenen galenischen Themen, alle bereitgestellt von Prof. R. Kinget.
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What is the best way to prepare a nasal solution containing 75 mg ephedrine HCl, 20 mg naphazoline HCl, 10 mg beclomethasone dipropionate, 60 mg sodium sulfacetamide, 0.01% cetrimide, and physiological serum up to 10 ml, given that the poor solubility of beclomethasone causes cloudiness and previous attempts to stabilize the solution using Tween, Tween and Span, Avicel, or lowering the pH to 5 did not yield satisfactory results?
How can a 3% EDTA ophthalmic solution be prepared?
What is the recommended dosage for ATP, and are there concerns regarding a high dose of 200 mg per capsule?
How can a stable solution containing 10% dimethicone and 10% essential oils in water be prepared for administration via spray for use on horses against horseflies, and is using Aerosil and Veegum to create a suspension as mentioned in the Technisch Magistraal Vademecum the best solution, or does an emulsifier exist to obtain a stable emulsion?
Why is a preparation of 0.2% chlorhexidine digluconate (from a 20% solution) in eucerin cum aqua up to 50g unstable, resulting in water separating from the cream after one hour of storage when using either self-prepared or Fagron-sourced eucerin cum aqua?
Which base should be used when chlorhexidine digluconate must be processed into a W/O cream, taking into account the incompatibility with sorbic acid and the O/W properties of chlorhexidine digluconate 20%?
What is the best way to incorporate 0.05% retinoic acid into sweet almond oil, considering that retinoic acid is insoluble in oil?
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