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Die Rezeptur‑Helpdesk enthält mehr als 1500 Fragen und Antworten zu verschiedenen galenischen Themen, alle bereitgestellt von Prof. R. Kinget.
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What is the best way to process dexpanthenol (100 mg per capsule) in capsules with pyridoxine 100 mg and riboflavine 100 mg, given that dexpanthenol is a thick, greasy, and sticky mass, and should Aerosil or another substance be used?
Is it possible to dissolve 5% minoxidil in a preparation containing 0.2% melatonin, 0.1% 17-alpha-estradiol, 35% propylene glycol, 30% ethanol 96%, and purified water up to 100%, and what are the considerations regarding the use, efficacy, and safety of topical melatonin and the inclusion of 17-alpha-estradiol in this solution?
How should a cyclosporine eye drop solution based on castor oil be prepared?
Given that phenylmercuric borate solution is unavailable, can it be replaced in the preparation of eye drops containing sodium fluorescein and oxybuprocaine hydrochloride?
Why must a trituration of menadione sodium bisulfite be prepared with mannitol, should preparations with fat-soluble vitamins also use mannitol as a filler, and must a 5% overdose always be used for a trituration?
How should the statement that "Liquid Phenol" or "phenolum liquefactum" contains 1 part phenol plus 10 parts water be interpreted, given that this results in approximately 90% phenol, and considering that the USP monograph defines liquid phenol as 89% phenol, 10% water, and a stabilizer, which suggests a preparation ratio of 9 parts phenol to 1 part water to obtain 10g of the substance?
What is a suitable formula for veterinary nasal drops containing 2.5 mg/ml of prednisolone acetate?
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