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Die Rezeptur‑Helpdesk enthält mehr als 1500 Fragen und Antworten zu verschiedenen galenischen Themen, alle bereitgestellt von Prof. R. Kinget.
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What is the best approach for preparing a sotalol 5 mg/ml pediatric suspension when the TMF formula is no longer available and the pure raw material is unobtainable, necessitating the use of sotalol tablets; specifically, can it be assumed that the sotalol hydrochloride in crushed tablets dissolves 100% in water to allow for a filtered solution with added citric acid and potassium sorbate, or is it preferable to create a suspension using SyrSpend SF PH4, which is known to be compatible and stable for three months?
How can the instability of a cream containing 3 g calamine, 5 g zinc oxide, 5 g sodium carbonate, 250 mg menthol, 250 mg phenol, 250 mg thymol, 5 g lanolin, 9 g glycerin, and 30 g cetomacrogol cream be resolved?
How can I prepare a 100 ml 17% EDTA solution for root canal irrigation, considering the solubility in water is approximately 1 in 11, and is it correct that the dentist recommends storing the solution in a plastic bottle instead of a glass one?
What is the best way to incorporate vitamin E in the form of alpha-tocopheryl succinate into a syrup for children at a dosage of 400 IU/5 ml?
Is a urea solution a suitable treatment for the discomfort caused by a "hairy tongue" and the associated bad breath?
What is the best way to prepare a formulation containing 2% erythromycin, 2% salicylic acid, 10% propylene glycol, and 40% isopropanol up to 100 ml, and is this clear solution stable and effective?
What are the guidelines regarding the use of contact lenses and cyclosporine eye drops?
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